Testosterone Replacement

Testosterone Replacement Therapy (TRT): What You Need to Know?

Testosterone Replacement Therapy (TRT) is a treatment designed to supplement or replace the body’s natural testosterone levels, which may decline due to aging, medical conditions, or other factors. Testosterone is a key hormone in the male body, responsible for regulating sex drive, muscle mass, bone density, and overall mood and energy levels.

TRT is typically recommended for men who have low testosterone levels (also known as hypogonadism) due to:

- Aging: Testosterone levels naturally decline with age, often starting around age 30.

- Medical Conditions: Conditions like hypogonadism, where the body doesn’t produce enough testosterone.

- Injury or Illness: Damage to the testes or pituitary gland can affect testosterone production.

- Hormonal Imbalances: Imbalances caused by various factors, including stress or obesity.

Men with low testosterone may experience symptoms such as:

- Reduced Sex Drive: Decreased libido and sexual performance.

- Fatigue: Persistent tiredness and lack of energy.

- Depression or Mood Changes: Increased irritability, anxiety, or feelings of depression.

- Loss of Muscle Mass: Decreased strength and muscle mass despite regular exercise.

- Increased Body Fat: Especially in the abdominal area.

- Decreased Bone Density: Leading to a higher risk of fractures.

- Cognitive Decline: Difficulty with concentration and memory.

TRT can be administered through various methods, including:

- Injections: Intramuscular injections of testosterone, typically given every 1 to 2 weeks.

- Gels and Creams:Topical application to the skin, allowing testosterone to be absorbed directly into the bloodstream.

- Patches: Applied to the skin, providing a steady release of testosterone throughout the day.

- Pellets: Implanted under the skin, providing a slow, continuous release of testosterone over several months.

- Oral Medications: Less common, but available in the form of testosterone tablets or lozenges.

While TRT can offer significant benefits, it’s important to be aware of potential risks and side effects, including:

- Increased Red Blood Cell Count: Can lead to thickened blood and increased risk of blood clots.

- Acne and Oily Skin: Increased oil production can lead to acne outbreaks.

- Sleep Apnea: Worsening of pre-existing sleep apnea conditions.

- Prostate Health: Potential for increased prostate growth or prostate cancer risks (though evidence is still inconclusive).

- Mood Swings: Some men may experience irritability or mood changes.

How to get started and what to expect at your appointment?

- Consultation: A thorough consultation with a healthcare provider or cosmetic professional to discuss your goals and assess your suitability for the treatment. Call our practice 210-622-2334 to book a consultation.

- Procedure: Ifyou are a good candidate for TRT and decide to move forward, we will draw labs that day.

- Follow up: You will have a follow up 3 weeks after your consultation to discuss lab results, dosing, etc. We will see you weekly for your TRT injection at our practice.

TRT Frequently Asked Questions:

How long does it take to see results from TRT?

Most men begin noticing improvements in energy, mood, and libido within 2–6 weeks. Physical changes such as increased muscle mass, reduced fat, and improved strength may take 8–12 weeks, with full benefits developing over several months of consistent therapy.

Is TRT a lifelong treatment?

It can be, depending on the cause of low testosterone. If your body cannot naturally produce adequate testosterone, long-term therapy may be recommended. Some men choose to continue TRT because of the significant improvement in their quality of life. Your provider will monitor you regularly and help determine the most appropriate long-term plan.

Can TRT affect fertility?

Yes. TRT can reduce sperm production and may temporarily impact fertility. Men actively trying to conceive should discuss alternatives with their provider, such as medications that support natural testosterone production rather than suppressing it.

Can TRT be used for bodybuilding or performance enhancement?

No. TRT is a medical treatment that is intended to treat the symptoms of low testosterone, while TRT may help improve muscle gains, it will not have the same effect of anabolic steroids. It is not prescribed for bodybuilding purposes. At Jules, therapy is strictly based on lab results, medical necessity, and symptom evaluation.

What symptoms can TRT help improve?

TRT can help improve:

• Low libido or reduced sexual performance

• Fatigue and decreased stamina

• Mood swings, irritability, or mild depression

• Loss of muscle mass or increased fat

• Difficulty concentrating

• Decreased strength or endurance

Many men report feeling more motivated, focused, and confident once levels are restored.

What labs are required before starting TRT?

Before beginning treatment, your provider will order comprehensive lab testing to evaluate testosterone, estrogen, PSA (prostate marker), red blood cell counts, thyroid function, metabolic markers, and overall health status. These labs ensure TRT is appropriate and safe for you. Follow-up labs are typically repeated a few weeks after starting to fine-tune your dosing.

What are the potential risks or side effects of TRT?

While TRT is safe when monitored properly, potential risks can include:

• Increased red blood cell count

• Acne or oily skin

• Worsening of sleep apnea

• Fluid retention

• Mood changes

• Prostate-related concerns

At Jules, your provider monitors your labs, symptoms, and overall health routinely to minimize risks and adjust your dosage as needed.

Who is not a good candidate for TRT?

TRT may not be suitable for men with:

• Prostate or breast cancer

• Severe untreated sleep apnea

• Uncontrolled heart disease or high red blood cell counts

• Unmanaged hypertension or diabetes

Your provider will review your medical history to determine if TRT is appropriate.

How is TRT administered?

TRT may be delivered through:

• Injections (most common and effective)

• Topical gels or creams

• Oral options (less common)

At Jules, most patients receive weekly injections for consistent levels and optimal results.